Transcription factors are proteins that bind to specific DNA sequences to regulate gene expression. They play important roles in various biological processes, including development, differentiation, and response to environmental stimuli. The activity of transcription factors is often regulated by different signaling pathways, such as the MAPK and PI3K pathways.
 
Signosis' TF activation profiling plate array I is a tool used to monitor the activation of 48 different transcription factors simultaneously. This array includes well-known transcription factors such as NFkB, AP1, HIF1, and p53, which are involved in a wide range of cellular processes. By monitoring the activation of multiple transcription factors at once, researchers can gain a more comprehensive understanding of the regulatory networks underlying gene expression and cellular signaling.
 
FA-1001 initial image's data was extracted from our customer's publication, NIH. (https://pubmed.ncbi.nlm.nih.gov/28378740/).