RANTES is a chemotactic protein for T cells, eosinophils, and basophils. RANTES is produced by circulating T-cells. The synthesis of RANTES is induced by TNFα and IL-1α. It plays an active role in recruiting leukocytes into inflammatory sites. With the help of particular cytokines that are released by T cells, Rantes also induces the proliferation and activation of certain natural-killer (NK) cells to form CC-Chemokine-activated killer cells. It is also an HIV-suppressive factor released from CD8+ T cells. RANTES increases the adherence of monocytes to endothelial cells.
 
Detection Range:
    16 - 1000 pg/mL
Sensitivity:
    8 pg/mL