Cytokines are extracellular signaling proteins produced by different cell types that act on target cells to modulate diverse cellular functions, such as recruiting specific cell types to the site of inflammation, increasing the activation and survival of immune cells, and suppressing cellular activity. Inflammation is the response of tissue to injury. During both acute and chronic inflammatory processes, a variety of soluble factors are involved in the cellular infiltrate, the cellular activation, and the systemic responses to inflammation. Cytokines are major determinants of inflammatory responses. Most cytokines are multifunctional molecules that elicit their effects locally or systemically through autocrine or paracrine signaling. Cytokines are involved in extensive networks that involve synergistic as well as antagonistic interactions and exhibit both negative and positive regulatory effects on various target cells. Therefore, profiling the expression patterns of cytokines can provide valuable insight into the underlying immunological mechanisms of inflammation. Signosis' Rat Inflammation ELISA Strip can quantitatively profile eight inflammation cytokines.
 
Detection Range:
    8 - 2000 pg/mL
Sensitivity:
    5 - 10 pg/mL