Musculoaponeurotic fibrosarcoma transcription factor (MAF) is a member of the basic leucine zipper family of transcription factors and plays an important role in cell differentiation, development, immune responses, and oncogenesis. The MAF luciferase reporter vector is designed to study the transcriptional activity of MAF. The vector contains a MAF DNA consensus binding site and TA minimal promoter upstream of a firefly luciferase reporter gene, which can specifically report MAF activity while maintaining a low basal level of transcription.