SRY-box transcription factor 9 (SOX9) is a transcription factor that plays a key role in regulating genes involved in chondrogenesis, cartilage and skeletal development, and sexual differentiation. The SOX9 luciferase reporter vector is designed to study the transcriptional activity of SOX9. The vector contains a SOX9 DNA consensus binding site and TA minimal promoter upstream of a firefly luciferase reporter gene, which can specifically report SOX9 activity while maintaining a low basal level of transcription.
 
The inclusion of a hygromycin resistance gene in the vector allows it to be used for stable cell line selection. Additionally, a GFP-tagged version of the vector is available for monitoring transfection efficiency. Maps of the vector, including hygromycin and GFP configurations, can be found in the product's image gallery.