SRY-box transcription factor 10 (SOX10) is a transcription factor that plays an essential role in the development of several cell types, especially in the nervous system, melanocytes, glial cells, and the enteric nervous system. The SOX10 luciferase reporter vector is designed to study the transcriptional activity of SOX10. The vector contains a SOX10 DNA consensus binding site and TA minimal promoter upstream of a firefly luciferase reporter gene, which can specifically report SOX10 activity while maintaining a low basal level of transcription.
 
The inclusion of a neomycin resistance gene in the vector allows it to be used for stable cell line selection. In addition, the vector also has a GFP-tag which can be used to monitor transfection efficiency. A map of the vector can be found in the product's image gallery.