Granulocyte colony-stimulating factor (G-CSF) is a colony-stimulating factor hormone. It is produced by a number of different tissues to stimulate the bone marrow to produce granulocytes and stem cells and to stimulate the bone marrow to release them into the blood. It also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils, as well as monocytes. G-CSF influences monocyte functions in an anti-inflammatory way. The stimulation of monocytes with G-CSF results in an attenuation of LPS-induced release of IL-1, TNFα, IL-12 and IL-18.
 
Detection Range:
    16 - 1000 pg/mL
Sensitivity:
    8 pg/mL