Vascular endothelial growth factor (VEGF) is one of the most potent and specific tumor-angiogenic factors. VEGF is used by oxygen-hungry cells to promote growth of blood vessels. It binds to specialized receptors on the surfaces of endothelial cells and induces to build new vessels. Most tumors produce VEGF and inhibition of VEGF-induced angiogenesis significantly inhibits tumor growth in vivo. A number of antiangiogenic drugs have shown to be capable of decreasing the number of vessels. VEGF expression correlates with microvessel density in a number of solid malignancies including carcinomas of the breast, lung, prostate, and colon.
 
Detection Range:
    16 - 1000 pg/mL
Sensitivity:
    8 pg/mL