Interleukin-17a (IL-17a) is a cytokine primarily produced by activated T cells to regulate local tissue inflammation. IL-17a can induce inflammatory cytokine production through the regulation of NFκB and MAPK family pathways. Elevated levels of IL-17a are associated with several chronic inflammatory diseases, including asthma, rheumatoid arthritis, and multiple sclerosis and has become an important potential target for their treatment. Understanding the conditions that alter the expression of this vital cellular messenger is important for unraveling the mechanisms of these and other diseases and for developing therapeutics.
 
Detection Range:
    16 - 1000 pg/mL
Sensitivity:
    8 pg/mL