ICAM-1 (Intercellular Adhesion Molecule-1) is a transmembrane glycoprotein primary expressed in immune and endothelial cells.  This typical low level expression of this protein is greatly increased by cytokine stimulation.  The traditional role of ICAM-1 is to stabilize intercellular adhesion; however ICAM-1 can also bind various immune-associated ligands, is the receptor for rhinovirus, and is believed to have a role in proinflammatory signal transduction.
 
Detection Range:
    16 - 1000 pg/mL
Sensitivity:
    8 pg/mL