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Pipetting Samples

miRNAs are small non-coding RNA molecules that regulate up to 30% of mammalian gene expression. They act as post-transcriptional regulators and bind to complementary sequences on target messenger RNA transcripts (mRNAs), resulting in translational repression or target degradation. So far, more than 400 miRNAs have been identified in the human genome and many of them are only different in one or a few nucleotides. Since the dysregulation of miRNA is associated with many diseases such as cancer, the research of miRNAs has important clinical implications.

Signosis offers a variety of innovative tools for the research of miRNAs. The miRNA Real-Time PCR, miRNA Northern Blot Assay, or miRNA Plate Assay can be used to analyze one specific miRNA of interest. In addition, multiple miRNAs can be profiled simultaneously with our miRNA Arrays. We also provide a wide selection of miRNA Luciferase Reporter Vectors, which can be used to study miRNA expression in cells.

miRNA Research

Our key research kits

Balanced Objects

Gene Expression Analysis

Gene Expression is the process by which information from a gene is used to direct the synthesis of a functional gene product. These products are often proteins. Gene expression analysis is critical to understand the functions of genes and its protein products, as well as to get a clearer picture of the complex regulatory networks that effect fundamental biological processes.

Signosis has a number of assay products for the gene expression study, including the cDNA Plate Arrays for monitoring the expression of genes that are up or down regulated by TFs, and the single cell PCR kits for analyzing gene expression, which allows direct analysis of cell lysates without RNA isolation prior assay.

Our Collections

Benefits

Simple 

DNA can be synthesized  directly in cell lysates without RNA preparation.  In addition, the detection is as simple as ELISA

Highly Sensitive Detection

Detected mRNA molecules are converted into multiple biotin-labeled cDNAs for sensitive detection

Quantitative Comparison

 The difference of two or more samples in gene expression can be quantitatively analyzed

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